Presentation modality of glycoconjugates modulates dendritic cell phenotype

Presentation Modality of Engineered Glycoconjugates Modulates Dendritic Cell Phenotype

Abstract Astrocytes Modulate Microglial Phenotype and Dendritic Cell-like Properties Astrocytes Modulate Microglial Phenotype and Dendritic Cell-like Properties Astrocytes Modulate Microglial Phenotype and Dendritic Cell-like Properties

ASTROCYTES MODULATE MICROGLIAL PHENOTYPE AND DENDRITIC CELL-LIKE PROPERTIES by Nischal K. Padala Microglia are the resident immune cells of the CNS. In the healthy CNS, they express negligible levels of MHC II molecules as well as co-stimulatory molecules CD40, CD80 and CD86 necessary for antigen presentation to and activation of T cells. Co-stimulatory molecule expression can be induced in iso...

MicroRNAs affect dendritic cell function and phenotype.

MicroRNA (miRNA) are small, non-coding RNA molecules that have been linked with immunity through regulating/modulating gene expression. A role for these molecules in T-cell and B-cell development and function has been well established. An increasing body of literature now highlights the importance of specific miRNA in dendritic cell (DC) development as well as their maturation process, antigen ...

Memory for modality of presentation: Within-modality discrimination.

Two experiments demonstrated that Ss are capable of making within-modality memory discriminations in both visual and auditory modalities. In Experiment I Ss studied mixed lists of pictures and labels representing common objects and were subsequently required to judge whether the original presentation was pictorial or verbal The high level of performance achieved on this task was unaffected by d...

Continuous mechanical contraction modulates expression of alveolar epithelial cell phenotype.

We have previously reported that mechanical distention of alveolar epithelial type II cells in culture favored the expression of the type I cell phenotype and inhibited the expression of the type II cell phenotype. The objective of the present study was to investigate the effects of continuous mechanical contraction on the expression of specific markers for the type I and type II cell phenotype...